The Xiao Lab
Recent News
Graduate student Martin Yepes featured on the cover of Leonella for his Bmore Micro arts!
Dr. Jie Xiao has been selected as the School of Medicine’s 46th recipient of the Johns Hopkins University Professors’ Award for Excellence in Teaching in Biomedical Sciences. This award is intended to recognize those faculty members whose investment in teaching School of Medicine students at both the pre- and/or postdoctoral levels is of the highest order.
Selected Recent Publications
Lyu Z, Yang X, Yahashiri A, Ha S, McCausland J, Chen X, Britton B, Weiss D, Xiao J. Third track model for coordination of septal peptidoglycan synthesis and degradation by FtsN in Escherichia coli. Nature Microbiology. 2025 May. doi: 10.1038/s41564-025-02011-w.
McQuillen R, Perez AJ, Yang X, Bohrer CH, Smith EL, Chareyre S, Tsui HT, Bruce KE, Hla YM, McCausland JW, Winkler ME, Goley ED, Ramamurthi KS, Xiao J. Light-dependent modulation of protein localization and function in living bacteria cells. Nat Commun. 2024 Dec 30;15(1):10746. doi: 10.1038/s41467-024-54974-9. PubMed PMID: 39737933; PubMed Central PMCID: PMC11685620.
Xinxing Yang, Ryan McQuillen, Zhixin Lyu, Polly Phillips-Mason, Ana De La Cruz, Joshua W McCausland, Hai Liang, Kristen E DeMeester, Cintia C Santiago, Catherine L Grimes, Piet de Boer, Jie Xiao, A two-track model for the spatiotemporal coordination of bacterial septal cell wall synthesis revealed by single-molecule imaging of FtsW, Nature microbiology, 2021, 6(5), p584-593
CH Bohrer, X Yang, S Thakur, X Weng, B Tenner, R McQuillen, B Ross, Matthew Wooten, Xin Chen, Jin Zhang, Elijah Roberts, Melike Lakadamyali, Jie Xiao, A pairwise distance distribution correction (DDC) algorithm to eliminate blinking-caused artifacts in SMLM, Nature methods, 2021, 18 (6), 669-677
Weng X, Bohrer CH, Bettridge K, Lagda AC, Cagliero C, Jin DJ, Xiao J. Spatial organization of RNA polymerase and its relationship with transcription in Escherichia coli. Proc Natl Acad Sci U S A. 2019 Sep 16;. doi: 10.1073/pnas.1903968116
Yang X, Lyu Z, Miguel A, McQuillen R, Huang KC, Xiao J. GTPase activity-coupled treadmilling of the bacterial tubulin FtsZ organizes septal cell wall synthesis. Science. 2017 Feb 17;355(6326):744-747
