(December 2022) Dr. Kelsey Bettridge‘s preprint “RNAP promoter search and transcription kinetics in live E. coli cells” is now available on BioRxiv!
(December 2022) Master student Ziqi Fu‘s preprint in collaboration with Dr. Ken Zhou and Dr. Monica Guo on “Differential Roles of positive and negative supercoiling in compacting the E. coli genome” is now available on BioRxiv!
(November 2022) Dr. Brooke Britton and Dr. Remy Yovanno‘s preprint in collaboration with Dr. Albert Lau and Dr. Zach Hensel on “Conformational changes in the essential E. coli septal cell wall synthesis complex suggest an activation mechanism” is now available on BioRxiv!
(September 2022) Dr. Jason Lyu‘s work in collaboration with Dr. David Weiss on “FtsN maintains active septal cell wall synthesis by forming a processive complex with the septum-specific peptidoglycan synthases in E. coli is now published in Nature Communications!
(September 2022) Master student Yuncong Geng‘s work in collaboration with Dr. Elijah Roberts on “A spatially resolved stochastic model reveals the role of supercoiling in transcription regulation is now published in PLoS Computational Biology!
(September 2022) Graduate student Nico Yehya was awarded the F31 Ruth L. Kirschstein Predoctoral Individual National Research Fellowship for his study of the impact of DNA topology on transcription. Congrats, Nico!
(August 2022) Dr. Joshua McCausland successfully defended his Ph. D. thesis on “FtsZ treadmilling guides the spatiotemporal distribution of E. coli cell wall synthases” and will be off to Stanford for his postdoctoral training in Dr. Christine Jacobs-wagner’s lab in sunny California. We will miss you, Josh!
(August 2022) Drs. Jason Lyu and Brooke Britton attend GRC Plant and Microbial Cytoskeleton Conference and present their research in Andover, NH.
(June 2022) Undergraduate student Anna Katherine Cooper from Mississippi State University, high school students Emily Liu from Advanced Math and Science Academy, MA, and SARE scholar Curelle Myles from Baltimore City College High School join our lab for summer research internships. Welcome!
(May 2022) Our preprint “Light-dependent modulation of protein localization and function in living bacteria cells” is now available on BioRxiv!
(March 2022) Dr. Brooke Britton was awarded the F32 Ruth L. Kirschstein Postdoctoral Individual National Research Fellowship for her study on bacterial cell division. Congrats, Brooke!
(December 2021) Our preprint “A spatially resolved stochastic model reveals the role of supercoiling in transcription regulation” is now available on BioRxiv!
(December, 2021) Our preprint “Gene regulation network inference using k-nearest neighbor-based mutual information estimation-Revisiting an old DREAM” is now available on BioRxiv!
(August, 2021) Our preprint “FtsN activates septal cell wall synthesis by forming a processive complex with the septum-specific peptidoglycan synthase in E. coli” is now available on BioRxiv!
(August, 2021) Dr. Gina Wang’s paper “Protein detection in blood with single-molecule imaging” has been published in Science Advances!
(June, 2021) Biostatistics masters student Ziqi Fu joins the lab. Welcome Ziqi!
(June, 2021) Our paper “A pairwise distance distribution correction (DDC) algorithm to eliminate blinking-caused artifacts in SMLM” has been published in Nature Methods!
(June, 2021) An author profile on Dr. Jie Xiao been published in Nature Methods to accompany “A pairwise distance distribution correction (DDC) algorithm to eliminate blinking-caused artifacts in SMLM” !
(May, 2021) First year PMB student Martin Yepes joins the lab. Welcome Martin!
(January, 2021) Our paper “Treadmilling FtsZ polymers drive the directional movement of sPG-synthesis enzymes via a Brownian ratchet mechanism” has been published in Nature Communications!
(January, 2021) Our paper “A two-track model for the spatiotemporal coordination of bacterial septal cell wall synthesis revealed by single-molecule imaging of FtsW” has been published in Nature Microbiology!
(January, 2021) Post doc Dr. Amilcar Perez joins the lab. Welcome Dr. Perez!
(September, 2020) Dr. Christopher H. Bohrer’s chapter on the complexity and importance of diffusion in bacteria has been published in Physical Microbiology, Advances in Experimental Medicine and Biology. Congratulations Chris!
(July, 2020) Dr. Kelsey Bettridge’s paper on the role of nucleoid-associated protein, HU, in organizing the bacterial chromosome has been published in Molecular Microbiology. Congratulations Kelsey!
(June, 2020) First year PMB student Frances Harris joins the lab. Welcome Fran!
(June, 2020) Post doc Dr. Brooke Britton joins the lab. Welcome Dr. Britton!
(May, 2020) Congratulations to Ryan McQuillen for completing his PhD!
(Feb, 2020) Congratulations to Christopher H. Bohrer for completing his PhD!
(Dec, 2019) The whole is greater than the sum of its parts– check out how this philosophy of Aristotle is exemplified by the way of the nucleoid-associated protein HU organizing the bacterial chromosome by Dr. Kelsey Bettridge and our collaborators Drs. and Sankar Adhya on BioRxiv.
(Nov, 2019) Bacterial cells do not have linear stepping motors, but they can still transport cargoes directionally. How? Find out from Josh McCausland and our collaborator Prof. Jian Liu‘s paper on BioRxiv.
(Nov, 2019) Dr. Xinxing Yang’s FtsW paper is now on BioRxiv! Check it out and see how smart E. coli cells use two tracks to organize their septal cell wall synthesis.
(Nov, 2019) Dr. Xinxing Yang gives a talk at the 6th Chesapeake Bay Area Single Molecule Biology meeting at University of Maryland.
(Sept, 2019) Ever dealt with fluorophore blinking in superresolution microscopy? It is worse than you think! Check out Chris Bohrer’s DDC algorithm to give you peace of mind. Now posted in BioRxiv.
(Sept, 2019) Xiaoli Weng’s paper on the spatial organization of RNA polymerase publishes in PNAS. Congratulations Xiaoli!
(Sept, 2019) Chris Bohrer gives a talk on his DDC algorithm at IBR retreat.
(Sept, 2019) Hopkins sophomore Hunter Hendrix joins the Xiao lab for undergraduate research. Welcome Hunter!
(Aug, 2019) Super Z-ring group meeting at Marion, MA. Fun and science-packed three days!
(July, 2019) SUSTECH senior Yao Tu joins the Xiao lab for summer research internship. Welcome Yao!
(June, 2019) U. Michigan senior Eric Donarski joins the Xiao lab for summer research internship. Welcome Eric!
(May, 2019) First year PMB student Nicolas Yehya joins the lab. Welcome Nico!
(September 25, 2018) Jie gives talk at Department of Biological Chemistry, University of Michigan, Ann Harbor, IL.
(September 9 – 12, 2018) Chris gives talk at Single-Molecule Bacteriology at 84th Harden Conference, Biochemical Society, Oxford University, U.K.
(September 5, 2018) Towson High school student Alice Liao joins the Xiao lab for her internship program. Welcome back Alice!
(September 1st, 2018) Jie and collaborator Elijah Roberts receive NSF funding to study gene regulation by chromosomal topological organization in E. coli.
(August 28 – September 1st, 2018) Kelsey presents research at Cold Spring Harbor Single Molecule Meeting, NY.
(August 25, 2018) End-of-the-summer pool party at Jie’s house.
(August 12-17, 2018) Xinxing and Jason present research at GRC Plant and Microbial Cytoskeleton, Andover, NH.
(August 13, 2018) Jie gives talk at GRC Plant and Microbial Cytoskeleton, Andover, NH.
(July 15-20, 2018) Xinxing, Jason and Gina present research at GRC Single Molecule Approaches to Biology, West Dover, VT.
(July 17, 2018) Jie gives talk at GRC Microbial Stress Responses, South Hadley, MA.
(July, 2018) Undergraduate students Yiwen Zhang from Peking University and Yiyan Lin from SUSTech university join the Xiao lab for summer research. Welcome Yiwen and Yiyan!
(June 9, 2018) Jie gives talk at annual Microbe meeting of American Society for Microbiology, Atlanta, GA.
(May 18, 2018) First year PMB student Drew Morley joins the Xiao lab. Welcome aboard Drew!
(May 12, 2018) Xiao lab attends the 3rd Chesapeake Bay Area Single Molecule Biology Meeting at Homewood campus, Johns Hopkins University.
(April 27, 2018) Jie gives student-invited seminar at Quantitative and Chemical Biology (QCB) Graduate Training Program at Indiana University, Bloomington.
(April 21, 2018) Ryan gives talk at Spotlight session at Annual Meeting of American Society for Biochemistry and Molecular Biology, San Diego, CA.
(April 14, 2018) Jie gives talk at the annual workshop on the Physical Basis on Cellular Memory and Adaptation, Barbados.
(April 13, 2018) Jie gives talk at Microbiology Society Annual Conference, Birmingham, U.K.
(March 20, 2018) Jie gives talk at NIH LMIG seminar.
(February 17, 2018) Jie and colleagues organize the inaugural Cell Biophysics Subgroup meeting at Biophysical Society Annual Meeting, San Fransisco
(January, 2018) BCMB first year student Claudia Carcamo joins lab for her second rotation.
(December, 2017) Congratulations to Xiaoli Weng for completing her PhD.
(June 16 – 20, 2017) Jie and colleagues organize Single-Cell Biophysics Thematic Meeting at Taiwan.
(May 9, 2017) Xinxing to receive the Paul Ehrlich Research Award in the Mountcastle Auditorium.
(April 8, 2017) Jie and colleagues organize the first Chesapeake Bay Area Single Molecule Biology Meeting.
(April, 2017) Xiaoli Weng is awarded an NSF student travel award to attend the Biophysical Society Thematic Meeting Single-Cell Biophysics in Taiwan.
(March, 2017) Xinxing Yang selected to receive Paul Ehrlich Research Award on Young Investigator’s Day.
(February, 2017) Kelsey Bettridge, Xiaoli Weng and Chris Bohrer attended Biophysical Society meeting in New Orleans, LA to present their research in platform talk and posters.
(January, 2017) Biomedical Engineering undergraduate student Carolyn Marar joins our research team.