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We are interested in taking single molecule measurements in living cells to study the organization, function, and dynamics of cellular processes.

Recent News

(April, 2017) Xiaoli Weng is awarded an NSF student travel award to attend the Biophysical Society Thematic Meeting Single-Cell Biophysics in Taiwan

(March, 2017) XINXING YANG SELECTED TO RECEIVE PAUL EHRLICH RESEARCH AWARD ON YOUNG INVESTIGATORS’ DAY

(Feb, 2017) Kelsey Bettridge, Xiaoli Weng and Chris Bohrer attended Biophysical Society meeting in New Orleans, LA to present their research in platform talk and posters.

(Jan, 2017) Biomedical Engineering undergraduate student Carolyn Marar joins our research team

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Upcoming Events

Single-Cell Biophysics Thematic Meeting  (June 16 – 20, 2017)

Xinxing to receive the Paul Enhrilich Research Award in the Mountcastle Auditorium. (May 9th, 2017)

CHESAPEAKE BAY AREA SINGLE MOLECULE BIOLOGY MEETING (February 8, 2017)

 

Select Publications

Yang, X., Lyu, Z., Miguel, A., McQuillen, R., Huang, K.C., and Xiao, J., GTPase activity-coupled treadmilling of the bacterial tubulin FtsZ organizes septal cell wall synthesis. Science, 2017. 355(6326): p. 744-747.

Coltharp, C., Buss, J., Plumer, T.M., and Xiao, J., Defining the rate-limiting processes of bacterial cytokinesis. PNAS, 2016. 113(8): p. E1044-53.

Buss J, Coltharp C., Shtengel G, Yang X, Hess H and Xiao J., Al multi-layered protein network maintains the stability of the FtsZ-ring and modulate constriction dynamics in E. coli, PLoS Genetics, 2015, Apr 7;11(4):e1005128.

Hensel Z.,Weng X., Lagda A., Xiao J., Transcription factor mediated DNA looping probed by high-resolution, single-molecule imaging in live E. coli cells, 2013, PLoS Biology, 11(6): e1001591.

Hensel Z., Feng H., Han B., Hatem C., Wang J., Xiao J., Stochastic expression dynamics of transcription factor revealed by single-molecule noise analysis, Nat. Struct. Mol. Biol. 2012,

Guo F., Huang T., Buss J., Coltharp C., Hensel Z., Xiao J., In vivo structure of the E. coli FtsZ-ring revealed by photoactivated Localization Microscopy (PALM), PLoS One, 2010, 5, e12680.

Research Topics